Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.
Identifieur interne : 000045 ( Main/Exploration ); précédent : 000044; suivant : 000046Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.
Auteurs : Thomas Menter [Suisse] ; Kirsten Diana Mertz [Suisse] ; Sizun Jiang [États-Unis] ; Han Chen [États-Unis] ; Cécile Monod [Suisse] ; Alexandar Tzankov [Suisse] ; Salome Waldvogel [Suisse] ; Sven M. Schulzke [Suisse] ; Irene Hösli [Suisse] ; Elisabeth Bruder [Suisse]Source :
- Pathobiology : journal of immunopathology, molecular and cellular biology [ 1423-0291 ] ; 2021.
Abstract
Since the outbreak of coronavirus disease 2019 (COVID-19), there has been a debate whether pregnant women are at a specific risk for COVID-19 and whether it might be vertically transmittable through the placenta. We present a series of five placentas of SARS coronavirus 2 (SARS-CoV-2)-positive women who had been diagnosed with mild symptoms of COVID-19 or had been asymptomatic before birth. We provide a detailed histopathologic description of morphological changes accompanied by an analysis of presence of SARS-CoV-2 in the placental tissue. All placentas were term deliveries (40th and 41st gestational weeks). One SARS-CoV-2-positive patient presented with cough and dyspnoea. This placenta showed prominent lymphohistiocytic villitis and intervillositis and signs of maternal and foetal malperfusion. Viral RNA was present in both placenta tissue and the umbilical cord and could be visualized by in situ hybridization in the decidua. SARS-CoV-2 tests were negative at the time of delivery of 3/5 women, and their placentas did not show increased inflammatory infiltrates. Signs of maternal and/or foetal malperfusion were present in 100% and 40% of cases, respectively. There was no transplacental transmission to the infants. In our cohort, we can document different time points regarding SARS-CoV-2 infection. In acute COVID-19, prominent lymphohistiocytic villitis may occur and might potentially be attributable to SARS-CoV-2 infection of the placenta. Furthermore, there are histopathological signs of maternal and foetal malperfusion, which might have a relationship to an altered coagulative or microangiopathic state induced by SARS-CoV-2, yet this cannot be proven considering a plethora of confounding factors.
DOI: 10.1159/000511324
PubMed: 32950981
PubMed Central: PMC7573905
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.</title><author><name sortKey="Menter, Thomas" sort="Menter, Thomas" uniqKey="Menter T" first="Thomas" last="Menter">Thomas Menter</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland, thomas.menter@usb.ch.</nlm:affiliation><country wicri:rule="url">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland</wicri:regionArea><wicri:noRegion>Switzerland</wicri:noRegion></affiliation></author><author><name sortKey="Mertz, Kirsten Diana" sort="Mertz, Kirsten Diana" uniqKey="Mertz K" first="Kirsten Diana" last="Mertz">Kirsten Diana Mertz</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Pathology, Cantonal Hospital Baselland, Liestal</wicri:regionArea><wicri:noRegion>Liestal</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Sizun" sort="Jiang, Sizun" uniqKey="Jiang S" first="Sizun" last="Jiang">Sizun Jiang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Monod, Cecile" sort="Monod, Cecile" uniqKey="Monod C" first="Cécile" last="Monod">Cécile Monod</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Tzankov, Alexandar" sort="Tzankov, Alexandar" uniqKey="Tzankov A" first="Alexandar" last="Tzankov">Alexandar Tzankov</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Waldvogel, Salome" sort="Waldvogel, Salome" uniqKey="Waldvogel S" first="Salome" last="Waldvogel">Salome Waldvogel</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neonatology, University Children's Hospital Basel UKBB, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Schulzke, Sven M" sort="Schulzke, Sven M" uniqKey="Schulzke S" first="Sven M" last="Schulzke">Sven M. Schulzke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neonatology, University Children's Hospital Basel UKBB, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Hosli, Irene" sort="Hosli, Irene" uniqKey="Hosli I" first="Irene" last="Hösli">Irene Hösli</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Bruder, Elisabeth" sort="Bruder, Elisabeth" uniqKey="Bruder E" first="Elisabeth" last="Bruder">Elisabeth Bruder</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2021">2021</date><idno type="RBID">pubmed:32950981</idno><idno type="pmid">32950981</idno><idno type="doi">10.1159/000511324</idno><idno type="pmc">PMC7573905</idno><idno type="wicri:Area/Main/Corpus">000304</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">000304</idno><idno type="wicri:Area/Main/Curation">000304</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">000304</idno><idno type="wicri:Area/Main/Exploration">000304</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.</title><author><name sortKey="Menter, Thomas" sort="Menter, Thomas" uniqKey="Menter T" first="Thomas" last="Menter">Thomas Menter</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland, thomas.menter@usb.ch.</nlm:affiliation><country wicri:rule="url">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland</wicri:regionArea><wicri:noRegion>Switzerland</wicri:noRegion></affiliation></author><author><name sortKey="Mertz, Kirsten Diana" sort="Mertz, Kirsten Diana" uniqKey="Mertz K" first="Kirsten Diana" last="Mertz">Kirsten Diana Mertz</name><affiliation wicri:level="1"><nlm:affiliation>Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Institute of Pathology, Cantonal Hospital Baselland, Liestal</wicri:regionArea><wicri:noRegion>Liestal</wicri:noRegion></affiliation></author><author><name sortKey="Jiang, Sizun" sort="Jiang, Sizun" uniqKey="Jiang S" first="Sizun" last="Jiang">Sizun Jiang</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name><affiliation wicri:level="4"><nlm:affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Department of Pathology, Stanford University, Stanford, California</wicri:regionArea><placeName><region type="state">Californie</region><settlement type="city">Stanford (Californie)</settlement></placeName><orgName type="university">Université Stanford</orgName></affiliation></author><author><name sortKey="Monod, Cecile" sort="Monod, Cecile" uniqKey="Monod C" first="Cécile" last="Monod">Cécile Monod</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Tzankov, Alexandar" sort="Tzankov, Alexandar" uniqKey="Tzankov A" first="Alexandar" last="Tzankov">Alexandar Tzankov</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Waldvogel, Salome" sort="Waldvogel, Salome" uniqKey="Waldvogel S" first="Salome" last="Waldvogel">Salome Waldvogel</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neonatology, University Children's Hospital Basel UKBB, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Schulzke, Sven M" sort="Schulzke, Sven M" uniqKey="Schulzke S" first="Sven M" last="Schulzke">Sven M. Schulzke</name><affiliation wicri:level="1"><nlm:affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Neonatology, University Children's Hospital Basel UKBB, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Hosli, Irene" sort="Hosli, Irene" uniqKey="Hosli I" first="Irene" last="Hösli">Irene Hösli</name><affiliation wicri:level="1"><nlm:affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author><author><name sortKey="Bruder, Elisabeth" sort="Bruder, Elisabeth" uniqKey="Bruder E" first="Elisabeth" last="Bruder">Elisabeth Bruder</name><affiliation wicri:level="1"><nlm:affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel</wicri:regionArea><wicri:noRegion>Basel</wicri:noRegion></affiliation></author></analytic><series><title level="j">Pathobiology : journal of immunopathology, molecular and cellular biology</title><idno type="eISSN">1423-0291</idno><imprint><date when="2021" type="published">2021</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Since the outbreak of coronavirus disease 2019 (COVID-19), there has been a debate whether pregnant women are at a specific risk for COVID-19 and whether it might be vertically transmittable through the placenta. We present a series of five placentas of SARS coronavirus 2 (SARS-CoV-2)-positive women who had been diagnosed with mild symptoms of COVID-19 or had been asymptomatic before birth. We provide a detailed histopathologic description of morphological changes accompanied by an analysis of presence of SARS-CoV-2 in the placental tissue. All placentas were term deliveries (40th and 41st gestational weeks). One SARS-CoV-2-positive patient presented with cough and dyspnoea. This placenta showed prominent lymphohistiocytic villitis and intervillositis and signs of maternal and foetal malperfusion. Viral RNA was present in both placenta tissue and the umbilical cord and could be visualized by in situ hybridization in the decidua. SARS-CoV-2 tests were negative at the time of delivery of 3/5 women, and their placentas did not show increased inflammatory infiltrates. Signs of maternal and/or foetal malperfusion were present in 100% and 40% of cases, respectively. There was no transplacental transmission to the infants. In our cohort, we can document different time points regarding SARS-CoV-2 infection. In acute COVID-19, prominent lymphohistiocytic villitis may occur and might potentially be attributable to SARS-CoV-2 infection of the placenta. Furthermore, there are histopathological signs of maternal and foetal malperfusion, which might have a relationship to an altered coagulative or microangiopathic state induced by SARS-CoV-2, yet this cannot be proven considering a plethora of confounding factors.</div></front></TEI><pubmed><MedlineCitation Status="In-Process" Owner="NLM"><PMID Version="1">32950981</PMID><DateRevised><Year>2021</Year><Month>01</Month><Day>21</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1423-0291</ISSN><JournalIssue CitedMedium="Internet"><Volume>88</Volume><Issue>1</Issue><PubDate><Year>2021</Year></PubDate></JournalIssue><Title>Pathobiology : journal of immunopathology, molecular and cellular biology</Title><ISOAbbreviation>Pathobiology</ISOAbbreviation></Journal><ArticleTitle>Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.</ArticleTitle><Pagination><MedlinePgn>69-77</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1159/000511324</ELocationID><Abstract><AbstractText>Since the outbreak of coronavirus disease 2019 (COVID-19), there has been a debate whether pregnant women are at a specific risk for COVID-19 and whether it might be vertically transmittable through the placenta. We present a series of five placentas of SARS coronavirus 2 (SARS-CoV-2)-positive women who had been diagnosed with mild symptoms of COVID-19 or had been asymptomatic before birth. We provide a detailed histopathologic description of morphological changes accompanied by an analysis of presence of SARS-CoV-2 in the placental tissue. All placentas were term deliveries (40th and 41st gestational weeks). One SARS-CoV-2-positive patient presented with cough and dyspnoea. This placenta showed prominent lymphohistiocytic villitis and intervillositis and signs of maternal and foetal malperfusion. Viral RNA was present in both placenta tissue and the umbilical cord and could be visualized by in situ hybridization in the decidua. SARS-CoV-2 tests were negative at the time of delivery of 3/5 women, and their placentas did not show increased inflammatory infiltrates. Signs of maternal and/or foetal malperfusion were present in 100% and 40% of cases, respectively. There was no transplacental transmission to the infants. In our cohort, we can document different time points regarding SARS-CoV-2 infection. In acute COVID-19, prominent lymphohistiocytic villitis may occur and might potentially be attributable to SARS-CoV-2 infection of the placenta. Furthermore, there are histopathological signs of maternal and foetal malperfusion, which might have a relationship to an altered coagulative or microangiopathic state induced by SARS-CoV-2, yet this cannot be proven considering a plethora of confounding factors.</AbstractText><CopyrightInformation>© 2020 S. Karger AG, Basel.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Menter</LastName><ForeName>Thomas</ForeName><Initials>T</Initials><AffiliationInfo><Affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland, thomas.menter@usb.ch.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mertz</LastName><ForeName>Kirsten Diana</ForeName><Initials>KD</Initials><AffiliationInfo><Affiliation>Institute of Pathology, Cantonal Hospital Baselland, Liestal, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jiang</LastName><ForeName>Sizun</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Chen</LastName><ForeName>Han</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Pathology, Stanford University, Stanford, California, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Monod</LastName><ForeName>Cécile</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Tzankov</LastName><ForeName>Alexandar</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Waldvogel</LastName><ForeName>Salome</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Schulzke</LastName><ForeName>Sven M</ForeName><Initials>SM</Initials><AffiliationInfo><Affiliation>Department of Neonatology, University Children's Hospital Basel UKBB, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hösli</LastName><ForeName>Irene</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Obstetrics and Antenatal Care, University Hospital Basel, University of Basel, Basel, Switzerland.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bruder</LastName><ForeName>Elisabeth</ForeName><Initials>E</Initials><AffiliationInfo><Affiliation>Pathology, Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>09</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>Switzerland</Country><MedlineTA>Pathobiology</MedlineTA><NlmUniqueID>9007504</NlmUniqueID><ISSNLinking>1015-2008</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">COVID-19</Keyword><Keyword MajorTopicYN="N">Chronic villitis</Keyword><Keyword MajorTopicYN="N">Malperfusion</Keyword><Keyword MajorTopicYN="N">Placenta</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>01</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2020</Year><Month>08</Month><Day>31</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2020</Year><Month>9</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2020</Year><Month>9</Month><Day>21</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2020</Year><Month>9</Month><Day>20</Day><Hour>20</Hour><Minute>38</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">32950981</ArticleId><ArticleId IdType="pii">000511324</ArticleId><ArticleId IdType="doi">10.1159/000511324</ArticleId><ArticleId IdType="pmc">PMC7573905</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Suisse</li><li>États-Unis</li></country><region><li>Californie</li></region><settlement><li>Stanford (Californie)</li></settlement><orgName><li>Université Stanford</li></orgName></list><tree><country name="Suisse"><noRegion><name sortKey="Menter, Thomas" sort="Menter, Thomas" uniqKey="Menter T" first="Thomas" last="Menter">Thomas Menter</name></noRegion><name sortKey="Bruder, Elisabeth" sort="Bruder, Elisabeth" uniqKey="Bruder E" first="Elisabeth" last="Bruder">Elisabeth Bruder</name><name sortKey="Hosli, Irene" sort="Hosli, Irene" uniqKey="Hosli I" first="Irene" last="Hösli">Irene Hösli</name><name sortKey="Mertz, Kirsten Diana" sort="Mertz, Kirsten Diana" uniqKey="Mertz K" first="Kirsten Diana" last="Mertz">Kirsten Diana Mertz</name><name sortKey="Monod, Cecile" sort="Monod, Cecile" uniqKey="Monod C" first="Cécile" last="Monod">Cécile Monod</name><name sortKey="Schulzke, Sven M" sort="Schulzke, Sven M" uniqKey="Schulzke S" first="Sven M" last="Schulzke">Sven M. Schulzke</name><name sortKey="Tzankov, Alexandar" sort="Tzankov, Alexandar" uniqKey="Tzankov A" first="Alexandar" last="Tzankov">Alexandar Tzankov</name><name sortKey="Waldvogel, Salome" sort="Waldvogel, Salome" uniqKey="Waldvogel S" first="Salome" last="Waldvogel">Salome Waldvogel</name></country><country name="États-Unis"><region name="Californie"><name sortKey="Jiang, Sizun" sort="Jiang, Sizun" uniqKey="Jiang S" first="Sizun" last="Jiang">Sizun Jiang</name></region><name sortKey="Chen, Han" sort="Chen, Han" uniqKey="Chen H" first="Han" last="Chen">Han Chen</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/CovidStanfordV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000045 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000045 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= CovidStanfordV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:32950981
|texte= Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:32950981" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a CovidStanfordV1
| This area was generated with Dilib version V0.6.38. |  |